Flexible workplace solutions
Mark Twain Plaza
Mark Twain Plaza in Edwardsville offers premium offices and coworking spaces. Located near popular dining spots like Peel Wood Fired Pizza and Cleveland-Heath, this workspace provides easy access to amenities and services including the U.S. Post Office and Edwardsville Police Department, enhancing productivity and business operations.
Get a quote
Receive personalized pricing and workspace solutions aligned perfectly to your business requirements.
Book a centre tour
Schedule a guided visit and experience our workspace facilities firsthand.
Book a meeting room
Reserve fully equipped meeting rooms ideal for presentations, client meetings, or team collaborations.
Book a day office
Secure a private office by the day—ideal for productive, focused work.
Book a cowork day pass
Enjoy flexible, immediate access to shared workspaces on demand.
Buy a virtual office
Establish a prestigious business address with professional mail and call-handling services.
Buy an access plan
Unlock flexible, convenient access to Regus locations globally with a membership tailored to you.
Download the app
Easily manage your workspace bookings and services anytime, anywhere with the Regus mobile app.

Your membership includes more than just workspace
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Widest product range
Our products are flexible, giving you the freedom to grow at your own pace without long-term commitments.
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Support team
Support staff to help you and your guests, from reception services to back-office functions such as IT.
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Community network
By joining Regus, you’ll gain access to a vibrant business community including networking events.
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The Regus app
Manage everything with the Regus mobile app, from bookings to controlling agreements, and getting support.
Products and service at Mark Twain Plaza
About Mark Twain Plaza
What makes this location special
Mark Twain Plaza in Edwardsville is strategically located for businesses seeking efficient operations. With proximity to the Edwardsville Police Department, your business benefits from enhanced security and compliance. The nearby U.S. Post Office ensures convenient mailing and logistics. Accessibility is a key advantage, supported by excellent transport links. Offices here provide a credible presence among local decision-makers, while coworking spaces foster collaboration and networking within the professional community. The close proximity to Anderson Hospital enhances employee well-being, and the area's commercial amenities contribute to operational efficiency, making Mark Twain Plaza an ideal choice for your business base.
You’re part of a much bigger network
Regus in Altonnorth_east
In Alton, businesses benefit from proximity to major employers like Alton Memorial Hospital and Lewis and Clark Community College, fostering strong industry connections. The Alton Regional Multimodal Transportation Center ensures seamless travel, making it ideal for serviced offices and coworking spaces, while the vibrant downtown area encourages collaboration and networking.
Amenities available
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Meeting Rooms
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Major Transport Links
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City/Town Center
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Common Areas
Where to find us
Address
101 W. Vandalia St. Suite 125, Edwardsville, IL, 62025, USA
24/7 Access
For private office and dedicated cowork customers
Nearby information

Prime Location in Edwardsville
Situated at 101 W. Vandalia St., our workspace offers a central location in the heart of Edwardsville, close to key amenities and institutions. Just minutes away from Southern Illinois University Edwardsville (SIUE), this area provides access to a vibrant academic community and opportunities for collaboration. Whether you're seeking flexible office space for a growing team or a professional environment to meet clients, this location ensures convenience and connectivity for your business needs.
Thriving Downtown Community
Edwardsville’s historic downtown area is a hub of activity, blending business with culture. The nearby Downtown Edwardsville Historic/Commercial District is home to municipal offices, local businesses, and long-standing institutions. This dynamic environment fosters networking and innovation, making it an ideal spot for a shared workspace. The district also features charming shops and eateries, perfect for lunch breaks or casual meetings, all within a short distance from your office.
Access to Government Services
Edwardsville serves as the seat of Madison County, providing easy access to government and judicial services. The Madison County Courthouse and Edwardsville City Hall are both located nearby, making this location advantageous for businesses that interact with public offices. Whether you need to handle legal matters or collaborate with local officials, having these essential services close by adds unparalleled convenience to your workday.
Vibrant Local Amenities
From cultural landmarks like the Wildey Theatre to vital services such as the Edwardsville Post Office, this location puts you at the center of the community. The Wildey Theatre, a historic performing-arts venue, offers films, concerts, and events that enrich the local culture. Additionally, Anderson Hospital’s Maryville campus is just a short drive away, providing peace of mind with access to quality healthcare. This well-rounded environment supports both business and personal well-being.
Nearby locations
The Regus difference
Joining Regus brings you the freedom, value and flexibility that every business needs:
A workspace for every budget
Pay only for the space that you use
Workspace when and where you need it
Space immediately available with no lead times
Simple, all-inclusive pricing with no capital expenditure required
Total flexibility in room options, sizes and setup
Say hello to a new way of working.
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